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Retro-mode imaging aids in examination of RPE alterations
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Retro-mode imaging may complement the investigation of alterations in retinal pigment epithelium in central serous chorioretinopathy, according to a study.
A retrospective review examined 48 eyes of 45 patients with central serous chorioretinopathy (CSCR). Patients were categorized in one of three groups: acute CSCR, chronic CSCR or resolved CSCR.
Patients underwent spectral-domain optical coherence tomography, fluorescein angiography, indocyanine green angiography and retro-mode imaging with confocal scanning laser ophthalmoscopy. Retro-mode images were used to evaluate retinal pigment epithelium (RPE) status by comparing the images with those of spectral-domain OCT, fluorescein angiography and indocyanine green angiography.
The study authors found that retro-mode imaging provided better topographic information of the RPE alterations. Spectral-domain OCT imaging was found to not be ideal for comprehension of the overall status of RPE lesions because numerous scans must be reviewed, according to the study authors.
To characterize deep retinal and RPE abnormalities in CSCR, retro-mode imaging was more effective than fluorescein angiography and indocyanine green angiography.
“It is difficult to make a treatment decision using retro-mode imaging,” the study authors said. “Therefore, retro-mode imaging may be helpful as an imaging technique to complement [fluorescein angiography], [indocyanine green angiography] and [spectral-domain] OCT.”
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