This article is more than 5 years old. Information may no longer be current.
Enhanced depth imaging OCT may improve visualization of small choroidal tumors
Click Here to Manage Email Alerts
Use of enhanced depth imaging spectral-domain optical coherence tomography in imaging small choroidal tumors offered improved visualization and revealed characteristics of choroidal melanoma vs. choroidal nevus, according to a study.
“Compared with similar-sized choroidal nevus, small choroidal melanoma is thicker and more often demonstrates subretinal fluid, subretinal lipofuscin deposition, and shagginess to the photoreceptor layer,” the study authors said.
The retrospective, comparative analysis examined 37 eyes diagnosed with small choroidal melanoma at a single center during a 1-year period. Mean patient age was 56 years.
All eyes were imaged using enhanced depth imaging OCT (EDI-OCT) and ultrasonography.
When compared with EDI-OCT, ultrasonography resulted in a 55% overestimation of small choroidal melanoma tumor thickness, the authors said.
Mean tumor thickness was determined to be 1,025 μm by enhanced depth imaging OCT (EDI-OCT) and 2,300 μm by ultrasonography. The mean difference of 1,275 μm was statistically significant (P < .001).
Statistically significant features for small choroidal melanoma detected by EDI-OCT in the study included intraretinal edema (P = .003), shaggy photoreceptors or loss of photoreceptors (P = .005), loss of external limiting membrane (P = .008), loss of inner segment-outer segment junction (P = .02), irregularity of inner plexiform layer (P = .04), and irregularity of ganglion cell layer (P = .04).
Click Here to Manage Email Alerts