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Outcomes poorer in cataract patients with nanophthalmos
Nanophthalmos eyes have worse refractive predictability and postoperative outcomes compared with relative anterior microphthalmos eyes and normal eyes, according to the results of a retrospective, case-control series.
Researchers evaluated patients who underwent routine cataract surgery between March 2007 and March 2010. Seventeen eyes with nanophthalmos, 29 eyes with relative anterior microphthalmos and 54 normal control eyes were included in the study. The mean age of the participants was 55 years in the nanophthalmos group, 73 years in the relative anterior microphthalmos group and 69 years in the control group.
Eyes with nanophthalmos had an axial length less than 20.5 mm and no morphologic malformation. Eyes with relative anterior microphthalmos had a corneal diameter of 11 mm or less, an anterior chamber depth of 2.2 mm or less, and an axial length of 20.5 mm or more. Control eyes had an axial length of 20.5 mm or more with a corneal diameter more than 11 mm or an anterior chamber depth more than 2.2 mm.
After phacoemulsification, refraction within 1 D of the target was achieved in 46% to 66% of the nanophthalmos eyes, 65% to 72% of the relative anterior microphthalmos eyes, and 90% to 98% of the normal eyes, according to the study.
At 2 months postoperative, differences in endothelial cell count among the three groups was not significant. Posterior capsule rupture occurred intraoperatively in two nanophthalmos eyes and no relative anterior microphthalmos eyes.