July 10, 2012
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No long-term morphological changes found after unilateral pediatric cataract surgery

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Pediatric patients who underwent cataract surgery were found to have an average endothelial cell loss of 9.2% and no difference in hexagonal cell percentage and coefficient of variation of cell area between operated and unoperated eyes after 12.5 years, according to a study.

The cross-sectional study examined 58 eyes of 58 patients who underwent unilateral pediatric cataract surgery between 1982 and 2004. The mean patient age at the time of cataract surgery was 38.2 months. The mean follow-up between surgery and assessments was 149.6 months.

Contralateral healthy eyes were evaluated as controls. All eyes with associated uveitis, glaucoma, micro-cornea, or history of ocular surgery or ocular trauma were excluded.

No statistically significant differences were observed related to endothelial cell loss between pseudophakic and aphakic eyes, between reoperated and non-reoperated eyes or among various surgical techniques.

The rate of endothelial cell loss found in the study was similar to the rate reported in the literature.