Prediction error high for IOL power calculation formulae in pediatric eyes

In children younger than 2 years old, prediction error remains high with all IOL power calculation formulae, according to a study.

The retrospective, comparative analysis examined 128 eyes of 84 children with congenital cataract who underwent primary IOL implantation. The study authors calculated the absolute prediction error of four commonly used IOL power calculation formulae.

With the SRK II, 27 eyes had an absolute prediction error within 0.5 D; 12 eyes had an absolute prediction error within 0.5 D with the Holladay, eight with the SRK T and five with the Hoffer Q.

The absolute prediction error with SRK II was significantly better than with the other formulae (P < .001).

Axial length was found to influence the absolute prediction error with the Holladay (P = .05) and the Hoffer Q (P = .002), while mean keratometry influenced prediction error with the SRK T (P = .03). These factors did not influence the SRK II.

“There is clearly a need to modify the current IOL power calculation formulae to make them more accurate and relevant for pediatric eyes,” the study authors said. “We also suggest continuous analysis of data to make adjustments to the IOL power calculation and thus customize the formula for pediatric eyes, which will give the least amount of absolute prediction error.”

Published by:

Sources/Disclosures

Collapse

Source:

Am J Ophthalmol. 2012:154(1);13-19.