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No statistical difference found between glaucoma patients, controls in tear osmolarity study
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COPENHAGEN, Denmark — Glaucoma patients who underwent topical treatment did not have a statistical difference in osmolarity measurements compared with a healthy control group, a study found.
“Glaucoma patients and age-matched controls don’t demonstrate statistically significant differences in Schirmer 1 values, OSDI score or tears osmolarity in this study,” the study authors said in a poster presented at the European Glaucoma Society meeting.
Theodoros Filippopoulos, MD, and colleagues at the Athens Vision Eye Institute conducted the prospective case-control study.
They examined a cohort of 30 glaucoma patients under topical treatment and 30 healthy controls with an average age of approximately 69 years. Measurements were taken with the TearLab osmolarity system (TearLab) and the Schirmer 1 test. Patients underwent a comprehensive eye examination to eliminate all external and corneal diseases other than dry eye. Patients also responded to the Ocular Surface Disease Index (OSDI) questionnaire.
Filippopoulos and colleagues found that “a cut-off value of 312 mOsm/L can be used to differentiate between those with good and suboptimal OSDI scores and/or Schirmer 1 test.”
- Disclosure: Filippopoulos has no relevant financial disclosures.