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Corneal cross-linking improves quality of life, refraction in patients with keratoconus
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CHICAGO – Corneal cross-linking improved visual function and keratometry values, according to a scientific poster presented at the American Society of Cataract and Refractive Surgery meeting here.
“Our results show that vision-related quality-of-life may improve after CXL, along with improvements in visual function and keratometric values,” Estra Asfuroglu, MD, and Ebru Toker, MD, wrote in the poster abstract.
Drs. Asfuroglu and Toker used the National Eye Institute Refractive Error Quality of Life Questionnaire (NEI-RQK) to analyze the effect of cross-linking on patients with progressive keratoconus.
The study included 26 eyes with mild to moderate keratoconus that were evaluated before treatment and up to 9 months after treatment. LogMAR uncorrected and best corrected visual acuity, corneal topography and corneal thickness were also studied.
Study results showed statistically significant improvement in nine subscales of the NEI-RQL (P < .001). UCVA improved from 0.28 to 0.21; BCVA improved from 0.15 to 0.10. Both improvements were statistically significant (P < .05).
The maximum K value diminished significantly from baseline by 1.36 D (P < .001).
Mean corneal thickness decreased significantly, by 24.4 μm at 1 month (P < .001). However, corneal thickness rebounded significantly between 3 and 9 months (P < .005), the authors said.
- Disclosure: Drs. Asfuroglu and Toker have no relevant financial disclosures.
- References: Shingleton BJ, Wooler KB, Bourne CL, O’Donoghue MW. Combined cataract and trabeculectomy surgery in eyes with pseudoexfoliation glaucoma. J Cataract Refract Surg. 2011;37(11):1961-1970.