Issue: July 25, 2012
April 10, 2012
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Study shows minimal refractive change after sutureless small gauge-PPV

Issue: July 25, 2012
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Sutureless small-gauge pars plana vitrectomy, or PPV, yielded negligible refractive changes such as increased astigmatism, a study found.

“Small-gauge sutureless PPV induces minimal re­fractive changes,” the study authors said. “The favorable refractive outcomes in this study should be considered along with other theo­retical advantages of sutureless small-gauge PPV.”

The retrospective study included 50 eyes of 50 patients with a mean age of 63 years. Thirty patients underwent 23-gauge PPV and 20 patients had 25-gauge PPV.

Study results showed that mean refractive changes from baseline were minimally significant: +0.5 D sphere (P = .03) and +0.25 D cylinder (P = .03). Mean change in axis of cylinder was 6° (P = .05) in the 23-gauge group. The maximum hyperopic shift was +0.5 D in spherical equivalent. The maxi­mum myopic shift was –1 D in spherical equivalent.

Mean changes in the 25-gauge PPV group were also minimally significant: +0.12 D sphere (P = .03) and +0.12 D cylinder (P = .03). Mean change in axis of cylinder was 17° (P = .015). The maximum hyperopic shift was +0.5 D in spherical equivalent. The maximum myopic shift was –1 D in spherical equivalent.

“There are various possible explanations for this observed refractive change,” the authors said. “PPV may result in an anterior movement of the intraocular lens position, re­sulting in a myopic shift. The effect of PPV on the crystalline lens is also a possible cause for postopera­tive refractive change.”

No intraoperative complications were reported.