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Study links axial length, cycloplegic refraction, keratometry in hyperopic amblyopes
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Axial length may be related to cycloplegic refraction and keratometry in hyperopic non-amblyopic and amblyopic eyes, according to a study.
“Thus, the pathophysiology of amblyopia in this setting does not involve a mismatch among these biometric variables,” the study authors said.
The authors set out to determine whether the pathophysiology of amblyopia affects the mathematical relationship between cycloplegic refraction and keratometry.
The prospective analysis included 23 children between the ages of 5 and 14 years old who were diagnosed with esotropia related to uncorrected hyperopia and underwent keratometry, optical biometry and cycloplegic refraction.
Investigators assessed the mathematical relationship in affected eyes with unilateral amblyopia. Refraction varied by at least two lines between eyes with refractive correction.
Study results showed that all children had a cycloplegic spherical equivalent of at least +2.75 D in at least one eye, 14 children were anisometropic by more than 1 D, and no children had myopia.
Data showed a strong correlation between the estimated and measured axial lengths of amblyopic eyes. The two values differed by 0.5 mm or less in 20 eyes and were within 0.9 mm in all eyes. A similar association has been seen in non-amblyopic eyes, the authors said.
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