September 12, 2006
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White-to-white distance potential predictor of pupil size changes

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LONDON — Pupil size can change depending on the white-to-white distance in eyes implanted with an iris-fixated IOL, according to a surgeon speaking here.

Sabine Buchner, MD, and H. Burkhard Dick, MD, PhD, studied 46 eyes implanted with Artisan iris-claw lenses (Ophtec) in order to evaluate intra-individual changes in pupil size. Dr. Buchner presented the results at the European Society of Cataract and Refractive Surgeons annual meeting.

Eyes were divided into two groups based on white-to-white measurements. Thirty-four eyes had a white-to-white measurement of less than 12.5 mm, and 12 eyes had a white-to-white measurement of 12.5 mm or more. All measurements were made using the IOLMaster (Carl Zeiss Meditec) under scotopic, mesopic low and mesopic high illumination conditions both pre- and postoperatively, with an enclavation distance of 8.5 mm, she said.

The researchers found that eyes with a white-to-white distance less than 12.5 mm had a 6.1% mean pupil size reduction, compared to a 14% mean reduction in eyes with a white-to-white distance of 12.5 mm or more.

The difference was particularly pronounced under mesopic low illumination, Dr. Buchner noted.

"A restriction of the pupil size in eyes with larger white-to-white distance under mesopic low and high illumination conditions can be expected and, therefore, may potentially reduce incidence of photic phenomena," she said.