February 25, 2009
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Wavefront-optimized PRK, LASIK did not induce significant higher-order aberrations

J Cataract Refract Surg. 2009;35(2):260-264.

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Wavefront-optimized PRK and LASIK proved equally effective and did not induce significant higher-order aberrations in a study. One percent of patients reported a subjective increase in aberrations, whereas 5% reported a subjective improvement.

The retrospective study included 100 eyes of 54 patients who underwent PRK and 100 eyes of 71 patients who underwent LASIK.

The WaveLight Allegretto Wave excimer laser was used in all cases. Outcome measures were uncorrected visual acuity, best corrected visual acuity, manifest refraction spherical equivalent, root mean square and grouped coefficient higher-order aberrations, and subjective reports of aberrations 3 months after surgery.

Data showed similar postoperative UCVA and BCVA in both groups. The difference between mean manifest refraction spherical equivalent after PRK (mean +0.11 D) and after LASIK (mean –0.19 D) was statistically significant. Changes in root mean square and grouped coefficient higher-order aberration values after PRK and LASIK were insignificant. Differences in those values between the PRK and LASIK group were also insignificant.