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Wavefront-guided similar to wavefront-optimized LASIK

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WASHINGTON — Wavefront-guided LASIK using the Allegretto Wave laser system has the same efficacy and safety profile as wavefront-optimized LASIK with the same laser, but the wavefront-guided procedure induced fewer higher-order aberrations, according to study results presented here.

At a symposium sponsored by laser-maker WaveLight, Stephen F. Brint, MD, FACS, presented results in 240 eyes that underwent either wavefront-optimized or wavefront-guided LASIK with the Allegretto Wave since September 2004. Wavefront-guided LASIK was perfomed in 122 of the eyes. Eyes with up to -7 D and -3 D of cylinder were randomized to treatment with wavefront-optimized or wavefront-guided profiles, Dr. Brint said.

“More than 90% of patients in both groups achieved 20/20 vision without glasses or contact lenses, and more than 60% achieved 20/16 or better,” Dr. Brint said at the symposium, according to a WaveLight press release. “For patients with few pre-existing higher-order aberrations, both platforms performed nearly identically.”

Guy M. Kezirian, MD, FACS, president of SurgiVision Regulatory Consultants Inc., the group that performed the study analysis, said “Preliminary results suggest that wavefront-guided treatments may offer certain advantages to a minority of patients with significant preoperative higher-order aberrations, such as trefoil and coma.”

A second study is under way to evaluate the safety and effectiveness of the Allegretto Wave for the treatment of mixed astigmatism, according to WaveLight.