November 09, 2007
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Wavefront-guided LASIK effective for re-treatments in highly aberrated corneas

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Performing wavefront-guided LASIK can effectively reduce residual higher-order aberrations and corneal irregularities in previous LASIK patients with highly aberrated corneas, a study found.

Jorge Alió, MD, PhD, and colleagues reviewed outcomes for 75 eyes of 59 patients who underwent customized corneal wavefront-guided LASIK re-treatments, including 37 eyes with significant night vision symptoms and 38 eyes with either decentration, irregular ablation profiles or flap complications (corneal complications group).

The researchers calculated ablation profiles using CSO corneal topography and the Schwind ESIRIS laser platform, according to the study.

At 6 months postop, mean uncorrected visual acuity had improved from 20/32 preoperatively to 20/25 among eyes in the night symptoms group and from 20/40 preoperatively to 20/30 among eyes in the corneal complications group. Best corrected visual acuity averaged 20/25 preoperatively and at 6 months follow-up in both groups, the authors reported.

Additionally, the efficacy index was 0.93 in the night symptoms group and 0.92 in the corneal complications group. The safety index was 1.1 in both groups, according to the study.

"Statistically significant improvement of total corneal higher-order aberrations, tilt and improvement of spherical aberrations and coma were observed, with corresponding improvement of [point spread function]," the authors said.

The study is published in the October issue of Journal of Refractive Surgery.