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Vitrectomy not shown to be associated with increased IOP

Retina. 2011;31(4):679-685.

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A study suggested that vitrectomy does not significantly increase IOP, even in the case of crystalline lens removal.

The retrospective cohort study analyzed the medical records of 101 eyes of 101 patients who underwent pars plana vitrectomy. Mean baseline IOP was 15.3 mm Hg, and mean follow-up was 49 months.

None of the eyes developed or required treatment for open-angle glaucoma. The mean final IOP was 15.8 mm Hg, and the mean incidence of an IOP increase of greater than 4 mm Hg was 7% at 4 years postop and 34% at 8 years postop.

Moreover, a subgroup of 66 patients with fellow eyes that did not undergo vitrectomy demonstrated no significant difference in the rate of IOP increase between treated and untreated eyes. Diabetes and pseudophakia were not associated with significant IOP increase.

Four eyes in the study were, however, newly diagnosed with ocular hypertension.