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Vitrectomy for uveitis: Success rate depends on type

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HANNOVER, Germany — Response to vitrectomy in uveitis varies according to the type of uveitis being treated, a study found.

Researchers here reviewed the charts of 58 patients who underwent pars plana vitrectomy (PPV) for cystoid macular edema (CME) in different forms of uveitis, including intermediate uveitis (42 patients; group A), chronic iridocyclitis in juvenile rheumatoid arthritis (14 patients; group B) and multifocal chorioretinitis (12 patients; group C). In none of the eyes had immunosuppressive or anti-inflammatory therapy, such as acetazolamide, led to CME regression. Follow-up ranged from 7 to 106 months.

A significant increase in visual acuity of 2 lines or more was observed in 50% of group A, 71% of group B and 42% of group C. Long-term follow-up suggested the best functional results were achieved in group A, the intermediate uveitis patients.

The authors suggest a multicenter study in a larger series of patients is needed to investigate the exact role the treatment plays in different forms of chronic uveitis. The study is published in the January issue of Der Ophthalmologe.