October 28, 2005
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Visante anterior chamber OCT comparable to Orbscan, ultrasound

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Visante OCT LASIK The Visante OCT had high sensitivity and specificity in detecting LASIK flaps, said John A. Vukich, MD. Image: Vukich JA

CHICAGO — Carl Zeiss Meditec introduced a device for noncontact anterior segment imaging during the American Academy of Ophthalmology meeting here. The Visante OCT allows high-resolution ocular coherence tomography imaging of anterior segment structures including the cornea, iris, angle and crystalline lens.

At a CME symposium sponsored by SLACK Incorporated and supported by an unrestricted grant from Zeiss, John A. Vukich, MD, reviewed the data from the U.S. clinical trial that led to Food and Drug Administration 510(k) approval of the device in October. In that multicenter trial, pachymetry measurements with the Visante were compared to those with a DGH ultrasound pachymeter and with the Bausch & Lomb Orbscan.

In 381 eyes, the Visante measured central corneal thickness consistently thinner than ultrasound and Orbscan, Dr. Vukich said, but the measurements correlated well. The researchers concluded that the Visante measurements were more precise than ultrasound and Orbscan, he said.

The ability of the Visante to detect LASIK flaps was also evaluated in the trial. The Visante had high sensitivity and specificity in detecting LASIK flaps, and is capable of producing images that are of use to the LASIK surgeon, Dr. Vukich said.

The Visante OCT can accurately measure corneal thickness without the need for immersion or anesthesia, according to information from Zeiss. The device can be used for full-thickness pachymetry as well as measurement of flap and stromal bed thickness immediately following LASIK, according to the company.

The device can also measure anterior chamber depth, anterior chamber angles and the angle-to-angle distance, the company said. In addition, IOLs and other implants in the anterior segment can be imaged and evaluated postoperatively.

At the same symposium, David Huang, MD, PhD, spoke about the physical principles of the Visante OCT. He said the device uses a laser wavelength of 1.3 µm, rather than the 0.8 µm wavelength used in posterior segment OCT imaging. This wavelength increases water absorption and decreases retinal exposure, allowing clear imaging of the anterior segment structures, Dr. Huang said.