September 05, 2002
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Vascular disease, disc hemorrhage may be linked

MALMO, Sweden — A significant relationship between use of platelet aggregation inhibitors and optic disc hemorrhages was found in a large population-based study here.

The study authors note that this finding may suggest a relationship between generalized vascular disease and optic disc hemorrhages, or it may indicate that platelet aggregation inhibitors prolong resorption of optic disc hemorrhages.

Researchers here screened citizens of Malmö who were between 57 and 79 years of age (32,918 people) to find individuals with undetected glaucoma. They found that optic disc hemorrhages were significantly more common in individuals taking platelet aggregation inhibitors (P < .0001) than in those not taking the inhibitors. No significant association between hemorrhages and antihypertensive agents, cholesterol-lowering medication or antidiabetic medication was observed.

The study is published in the Journal of Glaucoma.