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Two silicone hydrogel contact lenses induced similar corneal swelling in overnight-wear study
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Two types of silicone hydrogel contact lens caused similar amounts of central corneal swelling when subjects wore the lenses overnight, a study found.
Amir M. Moezzi, MSc, OD, and colleagues measured central corneal swelling after 8 hours of sleep in patients wearing silicone hydrogel contact lenses with high oxygen transmissibility. The study included 20 subjects who wore a comfilcon A lens (CooperVision) in one eye and a lotrafilcon A lens (CIBA Vision) in the contralateral eye. The researchers also repeated the study in a group of 20 subjects who wore a comfilcon A lens in one eye only and no lens in the contralateral eye.
Both contact lenses induced similar amounts of central corneal swelling (P > .05). In the second part of the study, the comfilcon A lens caused significantly more corneal swelling compared to non-lens-wearing control eyes (P < .05), according to the study authors. The swelling in the comfilcon-lens-wearing eyes was similar to that in previous reports of studies using lotrafilcon lenses, the authors said.
The study is published in the December issue of Eye & Contact Lens.