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Tube configuration can modify outflow resistance

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Outflow resistance of the Baerveldt glaucoma implant can be modified at the time of surgery by changing the tube configuration, a laboratory study suggests.

R. Reid Breckenridge, BS, and colleagues measured the outflow resistance of six tube configurations of the Baerveldt implant under constant pressure perfusion conditions. Pressures ranged from 2 mm Hg to 55 mm Hg.

At those pressures, mean outflow resistance in the normally configured seton was 0.41 mm Hg. Resistance remained unchanged after the addition of four venting slits. Mean outflow resistance was significantly increased with occlusion of the open seton tube using 3-0 and 4-0 Supramid sutures. When tubes were occluded with the sutures, adding venting slits significantly decreased mean outflow resistance.

The study is published in the October issue of the Journal of Glaucoma.