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Transscleral diode photocoagulation reduces IOP

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SINGAPORE — A transscleral diode laser procedure can lower intraocular pressure in patients with advanced, uncontrolled glaucoma, a pilot study here found.

Diode laser contact transscleral pars plana photocoagulation significantly reduced IOP up to 12 weeks postoperatively, the study authors reported.

Dr. Ching Lin Ho, FRCSEd, and colleagues used the procedure on 14 patients with visual acuity worse than 6/60 who had medically uncontrolled, refractory glaucoma.

Mean preoperative IOP was 41 mm Hg. One week after treatment with diode laser transscleral photocoagulation, 86% of patients experienced a significant decrease in IOP to a mean 29 mm Hg (P = 0.001) — a mean decrease of 12 mm Hg.

At 4 weeks follow-up, the mean IOP was 34 mm Hg. At 12 weeks, mean IOP was 32 mm Hg (P = 0.04).

Two patients who reported pain preoperatively reported cessation of pain following the procedure. Seven of 13 patients who required topical IOP-lowering medications preoperatively did not require them postoperatively.

The report is published in Clinical & Experimental Ophthalmology.