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Trabeculectomy in uveitic patients successful with antiproliferative adjuncts

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ATLANTA — Patients with uveitic glaucoma can have favorable outcomes after trabeculectomy with adjunctive antiproliferative agents, a study here found. Male sex was the only statistically significant risk factor for surgical failure, the study concluded.

Researchers here conducted a retrospective review of 44 eyes of 44 patients with uveitic glaucoma who underwent trabeculectomy with either adjunctive mitomycin-C or 5-fluorouracil. The probability of complete or qualified success (defined as intraocular pressure under 21 mm Hg with or without medication) was 78% at 1 year and 62% at 2 years. At 2-year follow-up, success rates were 39% in males and 71% in females (P = .02).

The study is published in the Journal of Glaucoma.