This article is more than 5 years old. Information may no longer be current.

Time domain and spectral domain OCT may lack acceptable agreement in measurements

Eur J Ophthalmol. 2011;21(5):566-572

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

Time domain and spectral domain optical coherence tomography may correlate well without demonstrating acceptable agreement between their measurements, suggesting that the devices cannot be used interchangeably, a study found.

In this prospective analysis, 123 eyes were scanned using Stratus TD-OCT (Carl Zeiss Meditec) and Cirrus SD-OCT model 4000 (Carl Zeiss Meditec). Sixty-eight of these eyes were without disease, 32 were glaucoma suspects, and 23 had glaucoma.

Average retinal nerve fiber layer thickness measurements were thinner on the SD-OCT device, comparatively, for normal subjects and glaucoma suspects (P < .001) but thicker in glaucoma patients; however, this difference was not statistically significant.

Good correlation was shown between the measurements in all three groups, although it was weaker in glaucoma patients.

Notably, measurements in the nasal quadrant in patients with glaucoma did not correlate, an occurrence that may be explained by the nasal quadrant being less commonly affected in early and moderate glaucoma, the study authors said.