November 21, 2007
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Thin preop corneal thickness not linked to post-LASIK keratectasia

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LASIK patients with a preoperative central corneal thickness of 500 µm or less do not have an increased risk of postoperative keratectasia, according to a study by researchers in California and Florida.

Andrew I. Caster, MD, and colleagues reviewed outcomes for 109 eyes of 69 LASIK patients who had a preoperative central corneal thickness between 452 µm and 500 µm. The attempted correction ranged from +3.13 D to –7.75 D, and patients had no known keratectasia risk factors, according to the study.

The researchers observed no clinical signs of keratectasia in any eye at any postoperative follow-up point. They also found no correlation between preoperative pachymetry and refractive change between 1 month and 12 months follow-up.

Additionally, investigators observed no statistically significant change in either mean spherical equivalent or manifest cylinder between 1 month and 12 months, according to the study.

"Double-angle vector analysis determined the directional shift in postoperative refractive cylinder was not statistically significant from zero (P < .05)," the authors said.

The study is published in the October issue of Journal of Refractive Surgery.