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Systemic evaluation of CNS disease warranted with uncommon ocular abnormalities
Systemic central nervous system evaluation may be warranted when a patient presents with uncommon bilateral ocular disease, authors of a case study suggest.
Carol Shields, MD, and others at Wills Eye Hospital in Philadelphia reported on a 10-month-old healthy male infant who presented with intermittent right exotropia. A dilated fundus exam showed a heavily pigmented mass within both optic discs. The discs were hypoplastic, and diffuse retinal pigment epithelial mottling around the optic discs was observed. Systemic evaluation, including thyroid function tests, pituitary gland hormone levels, adrenal gland hormone levels and magnetic resonance imaging of the brain revealed normal findings. After 1 year, the lesions remained stable, and the child was healthy with normal growth and development.
The study is published in the July issue of American Journal of Ophthalmology.