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Surgeon touts use of fibrin glue in pterygium procedures
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CHICAGO — The off-label use of human fibrin glue is the most important recent innovation in the surgical management of pterygium, according to a speaker here.
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"I think that evidence-based research in peer-reviewed journals have documented the benefits of using Tisseel (fibrin sealant, Baxter AG) in the context of pterygium management," Allan R. Slomovic, MD, MA, FRCS, said during Cornea Day held before the American Society of Cataract and Refractive Surgery meeting.
Dr. Slomovic spoke specifically about the commercially available Tisseel sealant, which is used for sealing, gluing and hemostasis. Ophthalmologists may use it in glaucoma, strabismus, corneal and LASIK surgeries, he said.
The added benefit of using the human fibrin adhesive is that "reduction of inflammation associated with the use of fibrin glue may reduce the pterygium recurrence rate," Dr. Slomovic said.
"One of the things that really impressed me using Tisseel glue was the relative lack of inflammation in these eyes," he said.
Dr. Slomovic said that a single center's retrospective chart review, which looked at the medical records of 65 eyes of 62 patients who underwent primary pterygium surgery with a fibrin glue, showed that two of those eyes experienced conjunctival graft dehiscense.
"Both of those patients admitted to premature removal of the eye pad and eye rubbing from day 1," Dr. Slomovic said.