September 12, 2007
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Surgeon: Opacification from silicone oil contact can occur in IOLs

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STOCKHOLM, Sweden — A case study showed the presence of silicone oil from pars plana vitrectomy with silicone oil remaining in the eye damaged a posterior chamber IOL enough to require explantation, according to a speaker here.

Milan G.J. Izak, MD, presented a case at the European Society of Cataract and Refractive Surgeons meeting in which a posterior chamber IOL required explantation following contact with silicone oil that remained in the eye after four previous pars plana vitrectomies.

A 20-year-old man presented with decreased vision from opacification of an Aqua-Sense hydrophilic acrylic posterior chamber IOL. He had previously undergone four pars plana vitrectomies, and silicone oil was left in the posterior chamber due to repeating preretinal re-proliferation, according to Dr. Izak.

The patient was then implanted with an Aqua-Sense posterior chamber IOL 26 months after the fourth vitrectomy. Eighteen months after the implantation, he presented with decreased visual acuity from lens opacification.

"A unique pattern of dystrophic calcification on the lens surface only was observed under light microscopy," Dr. Izak said.

Dr. Izak also noted that since this case in his hospital, he has observed other cases of opacification occurring with both silicone and hydrophilic acrylic IOLs when they were exposed to silicone oil.

"At the presence of silicone oil in the vitreous cavity, neither silicone nor hydrophilic acrylic IOLs should be implanted because of the risk of IOL opacification," Dr. Izak said.