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Supine, sitting IOP levels show similar increases at similar times

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Nocturnal elevations in intraocular pressure can be detected in healthy young adults whether they are sitting or supine, according to a study.

John H.K. Liu and colleagues with the Hamilton Glaucoma Center in La Jolla, Calif., studied 16 healthy volunteers to determine supine and sitting intraocular pressure (IOP) elevation levels. An 8-hour nocturnal/sleep period was assigned, and IOP was measured every 2 hours with volunteers in both sitting and supine positions over the course of 24 hours. Diurnal-to-nocturnal IOP change and the cosine fit 24-hour IOP rhythm were compared between the sitting and supine IOP data.

For both sitting and supine IOP, in the nocturnal period, mean IOP was significantly higher than in the diurnal/wake period. The mean difference between the trough and the peak was 3.8 mm Hg in the sitting position and 3.4 mm Hg in the supine position.

The study is published in the October issue of Investigative Ophthalmology & Visual Science.