February 11, 2009
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Subconjunctival anti-VEGF shows promise in the treatment of corneal neovascularization

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ROME — The use of subconjunctival bevacizumab may represent a promising method in the treatment of corneal neovascularization, according to a study at Charles University in Prague, Czech Republic.

At the winter meeting of the European Society of Cataract and Refractive Surgeons, Pavel Studeny, MD, presented the results of 17 eyes of 17 consecutive adult patients with corneal neovascularization who received subconjunctival injection of Avastin (bevacizumab, Genentech) in the dose of 0.75 mg per 0.03 mL. The mean age of the patients was 59 years (range, 25 years to 81 years).

"A considerable reduction of corneal neovascularization was obtained. No intraoperative complication occurred, and at 6 months, no side effects or complications have been reported by the patients," he said.