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Subclinical melanoma-associated retinopathy more common than previously thought

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Patients with cutaneous malignant melanoma are more likely to have symptoms suggestive of melanoma-associated retinopathy than previously thought, according to a study.

Claudia Pföhler and colleagues at The Saarland (Germany) University Hospital analyzed 28 patients with melanoma in stages 1 through 4 for the presence of subclinical melanoma-associated retinopathy (MAR). Seven patients had clinical signs and symptoms consistent with MAR, 18 had some indications and the remaining three showed no signs. No correlation existed between the symptoms and the stage of disease, tumor burden or S-100 level. The authors said findings suggested that increase MAR was found in patients with further advanced stages of the disease.

The study is published in British Journal of Dermatology.