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Study: Translocation treatment produced fixation, light sensitivity in exudative AMD patients
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Performing autologous retinal pigment epithelium-choroid sheet translocation may result in fixation and light increment sensitivity in patients with exudative age-related macular degeneration, according to a study by researchers in Germany.
Felix Treumer and colleagues at University of Schleswig-Holstein evaluated the fixation pattern and retinal sensitivity of 10 consecutive patients after removal of choroidal neovascularization and autologous retinal pigment epithelium-choroid translocation. They published their results in the September issue of Der Ophthalmologe.
Nine of the patients had exudative AMD and one patient had geographic atrophy, according to the study.
At 16.8 months mean follow-up, visual acuity had decreased from a range of hand motions to 0.2 preoperatively to a range of hand motions to 0.4, the authors reported.
However, four patients showed postoperative fixation on the graft. In addition, five patients showed light increment sensitivity over the graft on microperimetry, which was kept on a constant level in four patients.
"Light increment sensitivity can be kept on a constant level for at least 20 months," the authors said.
Postoperative complications included retinal detachment in three patients, proliferative vitreoretinopathy in one patient and choroidal neovascularization development in one patient, according to the study.