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Study: SLT lowers IOP in ocular hypertension, open-angle glaucoma

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Selective laser trabeculoplasty was safe and effective as a primary treatment for ocular hypertension and open-angle glaucoma in a small pilot study in Israel.

Shlomo Melamed, MD, and colleagues at the Goldschleger Eye Institute in Tel Hashomer evaluated 45 eyes of 31 patients with open-angle glaucoma or ocular hypertension that underwent selective laser trabeculoplasty (SLT). Ocular hypertension was defined as an intraocular pressure of 23 mm Hg or more on two consecutive measurements. IOP was measured at intervals out to 18 months postoperatively.

Mean IOP decreased by 7.7 mm Hg, from 25.5 mm Hg to 17.9 mm Hg, the authors reported. Two eyes did not respond to SLT, and three eyes required topical medications to control IOP. Complications included conjunctival redness and injection within 1 day postop in 30 eyes. One hour after surgery, an increase in IOP of more than 5 mm Hg was detected in five eyes.

The study is published in the July issue of Archives of Ophthalmology.