September 19, 2004
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Study: Sealed capsular irrigation system reduces secondary cataract at 1 year

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PARIS — A device that irrigates the capsular bag with sterile water following cataract removal reduced the development of capsular opacification when compared to control eyes at 1 year, according to a surgeon speaking here.

Anthony Maloof, MD, and colleagues in Sydney, Australia, conducted a study evaluating the PerfectCapsule (Milvella) sealed capsular irrigation (SCI) system in 25 cataract patients. Dr. Maloof presented the results here at a satellite symposium before the European Society of Cataract and Refractive Surgeons meeting.

The study compared rates of both anterior capsular opacification (ACO) and posterior capsular opacification (PCO) at 12 months in 14 study patients and 11 control patients. The capsular chambers of patients in the study group were selectively sealed using the SCI system and then irrigated with 10 mL of sterile water to eliminate any lens epithelial cells remaining following cataract extraction.

In all cases the capsulorrhexis was less than 5 mm, with a mean diameter of 3.9 mm, Dr. Maloof said.

At 12 months, patients in the study group had significantly lower ACO scores compared to the control patients (P = .03), he said. There were no cases of capsular phimosis in the study group and three cases in the control patients, Dr. Maloof said.

There was no statistically significant difference in PCO between the two groups, he added.

The SCI system is currently being investigated using sterile water to irrigate the capsular bag for up to 2 minutes immediately following lens removal. Other pharmacologic agents are also being considered, Dr. Maloof noted.