June 26, 2003
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Study: Ocular involvement in candidemia uncommon

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Ocular involvement in patients with systemic Candida species infections is more uncommon than previously believed, according to a study conducted by researchers at Vanderbilt University, Tennessee.

Sean P. Donahue, MD, and colleagues retrospectively reviewed inpatient hospital consultations performed by pediatric ophthalmologists over a 30-month period.

According to the study, 30 of 600 consultations were performed to rule out ocular findings in patients suspected or known to have Candida infections. No ocular findings consistent with endophthalmitis or chorioretinitis were seen. Nonspecific findings of multisystem organ failure were noted in one patient. One patient had vascular findings secondary to elevated pulmonary venous pressures.

The authors note their results contrast with studies performed 10 to 15 years ago. Further attention to risk factors associated with ocular infection is warranted, they conclude.

The study is published in the American Journal of Ophthalmology.