August 18, 2010
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Study: Novel contact lens device capable of measuring IOP and ocular pulse amplitude

J Glaucoma. 2010;19(6):382-390.

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A novel contact lens-embedded sensor may be capable of producing measurements of IOP and ocular pulse amplitude that are comparable to widely used devices, a study said.

In 12 eyes of 12 sitting subjects, measurements of IOP and ocular pulse amplitude from the contact lens-embedded sensor were similar to handheld and slit lamp-mounted configurations of the dynamic contour tonometer, according to the study.

Although measurements from all devices were greater with supine conditions, the contact lens sensor produced comparatively lower measurements of IOP and ocular pulse amplitude.

Researchers compared the measurements using analysis of variance and calculated the 95% limits of agreement.

The slit lamp-mounted and contact lens sensor comparisons had the smallest mean difference (0.7 mm Hg), while the contact lens and handheld sensors had the largest difference (–1.9 mm Hg), which was attributed to handheld measurement variability.

"This unique device is an important first step forward toward the ability to monitor IOP continuously and for prolonged periods in the human eye," the authors said. "To address some of the current limitations, future developments in microelectronics should lead to wireless sensors of smaller size capable of recording and storing data much like current cardiac monitors."