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Study: No correlation between refractive indices, CCT

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STOCKHOLM, Sweden — No relation between refractive error and central corneal thickness was found in a study of patients who underwent laser keratorefractive surgery, a physician said at the European Society of Cataract and Refractive Surgeons meeting.

Shiva Mehravaran, MD, and colleagues evaluated the correlation of CCT with refractive error and keratometry to determine if it can serve as a bias in IOP measurement studies. The cross-sectional observational study examined the right eyes of 340 patients.

Dr. Mehravaran and colleagues found the mean cycloplegic spherical equivalent was –3.2 ± 2.3 D and the mean CCT was 549.5 ± 33.6 µm. No other parameters, including age, sex or amount of refractive error, showed significant correlation with CCT in the study population, she said.

"In this group of refractive surgery patients, we didn't see any significant correlation with the corneal thickness — only eight patients were borderline significant," she said. "You can say that the correlation that they're finding between IOP and central corneal thickness is not biased by the refractive indexes of the patients in this study."