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Study links early rise in IOP after diabetic vitrectomy to poor visual outcomes

Indian J Ophthalmol. 2011;59:37-40.

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An early rise in IOP following pars plana vitrectomy may be associated with poor visual outcomes, a study found.

The longitudinal, prospective study sought to determine the incidence and risk factors for an early spike in IOP, as well as its correlation with later visual outcomes, in 73 patients with proliferative diabetic retinopathy.

IOP and best corrected visual acuity were recorded at day 1, week 1 and months 1, 3 and 6 postop. A significant increase, defined as IOP of at least 30 mm Hg, occurred in 20.5% of patients at day 1. Risk factors for this increase included intraoperative fibrovascular frond removal, which was performed in 52.1% of patients, lens removal and intraoperative vitreous bleed.

Early rise in IOP correlated with a consistently raised IOP, defined as greater than 21 mm Hg during the first three follow-up exams. Moreover, IOP at day 1 and final BCVA were also positively correlated.

This correlation between early IOP and BCVA at 6 months postop may result from the persistently raised IOP, which often requires medical therapy or surgery that may cause poor visual acuity, the study authors said.