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Study: Levator muscle function abnormalities may be factor in developing involutional blepharoptosis
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Because a directly proportional decrease in levator function and eyelid height may be observed among patients with involutional blepharoptosis, abnormalities in levator muscle function appear to be a contributing factor for developing the disorder, a recent study suggests.
Luciano S. Pereira, MD, and colleagues in California and Ohio reviewed medical records of 136 patients with acquired blepharoptosis and performed multivariate linear regression analysis of levator function, margin reflex distance, age and gender to evaluate the possible correlation between ptosis severity and levator muscle function.
A significant correlation was found between margin reflex distance, which averaged 1 mm, and levator function, which averaged 15 mm (P < .001).
On average, the investigators observed a 0.5-mm reduction in levator function for each 1-mm decrease in margin reflex distance. This correlation functioned independently of all other variables, according to the study, published in the June issue of American Journal of Ophthalmology.