February 28, 2008
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Study finds variations in CCT between pseudoexfoliation glaucoma, ocular hypertension

Central corneal thickness can vary between patients with different types of glaucomas and may be particularly important when evaluating cases of pseudoexfoliation glaucoma or ocular hypertension, according to a study by researchers in Greece.

Spiridon Gorezis, MD, and colleagues at the University of Ioannina measured the central corneal thickness (CCT) for 60 eyes with primary open-angle glaucoma and 50 eyes with pseudoexfoliation glaucoma and compared the measurements with those for 60 normal control eyes.

"Central corneal thickness was significantly thinner in cases with pseudoexfoliation glaucoma (P < .0001) and significantly thicker in cases with ocular hypertension (P < .0001)," the authors said.

"These results agree with the literature, strengthening the position that central corneal thickness varies in different types of glaucoma and, therefore, is a parameter that should be taken under consideration, especially when evaluating cases of pseudoexfoliative glaucoma and ocular hypertension," they said.

The study is published in the January/February issue of Ophthalmic Surgery Lasers & Imaging.