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Study finds patients with polypoidal choroidal vasculopathy benefit from PDT

Graefes Arch Clin Exp Ophthalmol. 2010;248(9):1233-1239.

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Photodynamic therapy in patients with polypoidal choroidal vasculopathy can improve best corrected visual acuity, especially when certain conditions are present, according to a study.

Of the 181 eyes of 181 patients that underwent PDT, 55 eyes had improved best corrected visual acuity and 110 eyes maintained BCVA at 1 year follow-up.

Mean logMAR BCVA improved from 0.29 to 0.43.

"Better BCVA can be expected 1 year after PDT in eyes with [polypoidal choroidal vasculopathy] showing better initial BCVA, relatively small lesions on indocyanine green angiography and no subfoveal polypoidal lesion before PDT," the study authors wrote.

Patients underwent a maximum of four additional PDT sessions if needed for up to 9 months after initial treatment.