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Study finds no significant changes in corneal biomechanics following corneal cross-linking
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CHICAGO — Biomechanical characteristics in keratoconus cases that underwent corneal collagen cross-linking with riboflavin (C3-R) showed no major changes at 12 months following treatment, a study found.
"Our study suggests that no significant differences in corneal biomechanical characteristics can be detected 1 year after treatment," Nicola Rosa, MD, and colleagues said in a poster presented at the joint meeting of the American Academy of Ophthalmology and Middle East Africa Council of Ophthalmology. "Corneal cross-linking seems to avoid the progression of keratoconus during a 12 months follow-up."
The study examined 23 eyes of 23 patients with keratoconus with a mean age of 21.82 years. Patients underwent corneal collagen cross-linking with riboflavin (C3-R).
Both before and after treatment up to 12 months, corneal hysteresis (CH) and corneal resistance factor (CRF) were measured with the Ocular Response Analyzer (Reichert), Dr. Rosa and colleagues said.
Before treatment, CH was 7.77 mm Hg; at 12 months it was 7.49 mm Hg.
Prior to treatment, CRF was 6.43 mm Hg; at 12 months it was 6.21 mm Hg .