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Study finds monofixation can be misclassified on single assessment
Am J Ophthalmol. 2010;150(1):16-22.
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Classifying sensory monofixation in intermittent exotropia depends on the stereotest used, and misclassification can occur if conclusions are based on a single administration of a test, a study showed.
Researchers conducted a retrospective case review of children with intermittent exotropia who were assessed using Preschool Randot, Frisby and Titmus stereoacuity tests.
Of the subjects measured by all three tests during one exam, 44 children aged 3 years to 16 years were identified with intermittent exotropia, and sensory monofixation occurred in 36% using Preschool Randot, in 48% using Titmus and in 55% using Frisby. Monofixation was defined as any stereoacuity value worse than age-referenced normal populations.
Of the subjects measured by one or more tests on two sequential visits, 92 children aged 2 years to 17 years were identified with near stereoacuity, and misclassification of monofixation occurred in 5% using Preschool Randot, in 13% using Titmus and in 23% using Frisby. Misclassification was defined as a stereoacuity threshold consistent with monofixation on the first examination, followed by a stereoacuity threshold consistent with bifixation (at least 40 arc seconds) on the second examination.
Researchers concluded potential misclassification of monofixation needs to be considered both in clinical practice and in study design.
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