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Study: Factors identified for better visual prognosis for myopic CNV patients treated with PDT

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Among patients treated with photodynamic therapy for myopic choroidal neovascularization, younger age, larger lesions and better best corrected visual acuity at baseline may be associated with better visual outcomes in the long term, according to a prospective study by researchers in Spain.

"The poorer results for elderly patients with lower initial BCVA might lead us to consider other therapeutic approaches," the study authors said.

José M. Ruiz-Moreno, MD, and colleagues at University of Castilla-La Mancha and Alicante Institute of Ophthalmology evaluated visual outcomes for 39 eyes of 36 highly myopic patients treated with PDT. BCVA and fluorescein angiography measurements were obtained in 3-month intervals over 48 months' follow-up.

At baseline, BCVA averaged 9 ETDRS lines, the authors noted.

Subsequently, BCVA averaged 10.4 lines at 12 months, 9.7 lines at 24 months, 9.6 lines at 36 months and 9.6 lines at 48 months.

Multiple regression analysis showed that BCVA improvement was significantly associated with BCVA at baseline (P < .002), lesion diameter (P < .04) and age (P < .04), according to the study, published in the June issue of British Journal of Ophthalmology.