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Study: Different medical therapies after cataract extraction yield similar results
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SAN DIEGO — No statistically significant differences for a variety of outcomes were found between three groups of patients receiving different combinations of pharmacological agents after cataract surgery, according to a study presented here.
Results were presented in a poster at the American Society of Cataract and Refractive Surgery meeting by Hon-Vu Q. Duong, MD, and colleagues.
The study found no statistical differences among patients who instilled standard drugs after cataract surgery, those who instilled antimicrobial and topical NSAIDs, and those who received intraoperative steroid injections of an antimicrobial and NSAID agent.
In the prospective, randomized, single-masked study, researchers compared IOP differences, degrees of anterior inflammation and macular edema among patients who instilled prednisone 1%, a postoperative injection of triamcinolone followed by gatifloxacin and bromfenac (Ista Pharmaceuticals), or only gatifloxacin and bromfenac.
"Preoperative evaluation included a comprehensive ophthalmic exam and baseline macular OCT," Dr. Duong and colleagues said. "Postoperative data included IOP and direct visual anterior segment cell count at 1-day, 1-week and 1-month postoperative periods."
- Disclosure: Dr. Duong has no direct financial interest in the products discussed in this article, nor is he a paid consultant for any companies mentioned.