February 26, 2007
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Study challenges belief that hydrophilic acrylic IOL opacification begins on lens surface

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Researchers in England found subsurface deposits in a number of explanted opacified hydrophilic acrylic IOLs. The findings challenge the belief that opacification begins on the optic surface of these lenses, the study authors said.

Nathaniel E. Knox Cartwright, of Bristol Eye Hospital, and colleagues examined 14 explanted Hydroview H60M IOLs (Bausch & Lomb) using scanning electron microscopy. Subsurface deposits were seen in all lenses. Wavelength-dispersive X-ray spectroscopy, performed on two opacified lenses, confirmed the presence of both calcium and phosphorous in the deposits, according to the study.

However, deposits broke only onto the surfaces of more densely opacified lenses, the authors noted.

The study is published in the February issue of the British Journal of Ophthalmology.