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Study: Bupivacaine plus lidocaine comparable to levobupivacaine, ropivacaine for cataract surgery
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When administered for peribulbar anesthesia, bupivacaine and lidocaine combined shows comparable efficacy to levobupivacaine alone and ropivacaine alone for use during phacoemulsification cataract surgery, according to a study by researchers in Turkey.
Mehmet Borazan, MD, and colleagues at Baskant University School of Medicine in Ankara compared the safety, efficacy and blocking quality of the anesthetic mixtures in a study involving 105 patients. Investigators randomly assigned three groups of 35 patients to receive a 1:1 mixture of bupivacaine and lidocaine (group 1), levobupivacaine only (group 2) or lidocaine only (group 3).
Although ocular movement and verbal pain scores differed slightly between the three groups, the authors noted that none were clinically significant.
The study is published in the December issue of Acta Ophthalmologica Scandinavica.