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Study: BRVO symptoms usually appear in the morning

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Patients who develop branch retinal vein occlusions usually begin experiencing symptoms during the morning hours, according to a study by researchers in South Korea.

Jaeryung Oh, MD, PhD, and colleagues at the Korea University College of Medicine, Seoul, questioned 72 consecutive patients with newly diagnosed branch retinal vein occlusion (BRVO) about the timing of the onset of symptoms.

"Analysis of the diurnal variation of symptom onset showed a distribution with the peak in the period from 6 a.m. to noon compared with all the other time periods," the authors said.

In the multivariate analysis, the researchers also found that superior retinal involvement was the only factor influencing the timing of the onset of symptoms, according to the study.

"Patients with symptomatic BRVO frequently noted their visual deterioration in the morning, which is the same as the other types of ocular and systemic vascular disease," the study authors said. "Our results may be helpful for understanding the pathophysiology of BRVO. Our findings require conformation and further studies on this subject are certainly warranted."

The study is published in the June issue of Ophthalmologica.