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Study: AcrySof IOLs have low capsulotomy rate
CHANDIGARH, India — Alcon AcrySof IOLs had the lowest rate of posterior capsular opacification and Nd:YAG capsulotomy in a study here comparing PMMA, silicone and acrylic IOLs.
Jagat Ram, MD, and colleagues studied 340 patients who underwent phacoemulsification and implantation of a PMMA (Pharmacia or Domilens), acrylic (Alcon AcrySof) or silicone (Allergan SI 30 NB) IOL. Of the patients, 184 received PMMA IOLs, 95 received silicone IOLs and 61 received acrylic IOLs.
Of the acrylic IOL patients, 6.5% developed posterior capsular opacification (PCO). Only one of those four patients required Nd:YAG capsulotomy.
Of the patients receiving PMMA IOLs, 21.7% developed PCO, 65% in the first 6 months postop. Nd:YAG capsulotomy was required in 45% of the PMMA patients who developed PCO.
Of the patients receiving silicone lenses, 26.6% developed PCO. In this group, PCO took longer to appear, developing in a majority of the group 18 months postop. However, 60% of these patients required Nd:YAG capsulotomies as well.
The authors did note, however, that the silicone IOLs used had polypropylene haptics, which may have indirectly resulted in a higher percentage of PCO than if they had used silicone IOLs with PMMA haptics.
The study appears in the Sept./Oct. issue of Ophthalmic Surgery & Lasers.