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Stent lowers IOP in 50% of advanced glaucoma patients
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NEW ORLEANS — A trabecular micro-bypass stent reduced IOP in more than 50% of patients with advanced cases of glaucoma, a surgeon said here.
The study examined the iStent trabecular micro-bypass stent (Glaukos), which was implanted in 45 subjects with high IOP who had failed conventional glaucoma surgery or were poor candidates for glaucoma surgery, study author Carlo E. Traverso, MD, said at the annual American Academy of Ophthalmology meeting.
"With a population of patients who had failed on prior therapy and/or surgery or considered poor candidates for filtering procedures, the implantation of the stent resulted in a statistically significant reduction both in mean IOP and IOP-lowering medications," Dr. Traverso said.
Subjects in the prospective, multicenter study had open-angle glaucoma with a baseline IOP of 25.5 ± 6.39 mm Hg on maximal tolerated medical therapy, he said.
One-year interim results found that IOP was 18.8 ± 4.74 mm Hg. At 1 year, 55%, or 23 of the 43 patients who remained in the study, had IOP less than 21 mm Hg with a decrease or no change in medications. Those patients had no need for further filtration surgery, Dr. Traverso said. Of those, 79% had IOP less than 21 mm Hg with medication, while 21% had IOP of less than 21 mm Hg and no glaucoma medications.