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Standardization of parameters for glaucoma surgical success needed for accurate comparisons

Ophthalmology. 2010;117(1):18-23.

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A wide range of definitions of surgical success in glaucoma studies affects the recorded success rate of trabeculectomy, a study examining published literature on the subject reported.

"Standardization of published outcome parameters after glaucoma surgery is essential to allow meaningful comparisons between different study reports," the study authors said.

Of 100 publications examined in the study, 92 different IOP-related definitions of success were found.

"Over a recent 5-year period, there were nearly as many different definitions of success after glaucoma surgery as publications on the subject," the authors said. "The definition used markedly affects the quoted success rate after trabeculectomy, making interpretation of and comparison between published results extremely difficult."

The study was a systematic review of published studies through PubMed for a 5-year time span. Definitions were applied to the authors' retrospective cohort of 100 patients who had undergone trabeculectomy. Using these definitions, success rates for these 100 trabeculectomies at 3 years follow-up ranged from 36% to 98%.