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Standard automated perimetry, clinical findings may predict glaucomatous optic neuropathy
Invest Ophthalmol Vis Sci. 2009;50(2):674-680.
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A classification tree model that uses standard automated perimetry thresholds and their location in the visual field may help determine which patients are most at risk for poor outcome from progressive glaucomatous optic neuropathy.
In a study using classification and regression tree analysis involving 168 individuals with high-risk ocular hypertension or early glaucoma, location of visual field findings on perimetry was predictive of whether the eye would exhibit glaucomatous optic neuropathy. Eleven of the 26 locations in the inferior field were determined to be important in whether a patient had optic neuropathy, compared with six locations of 27 in the superior field with high importance and 14 of 27 with low importance.
Visual field location may provide valuable information on risk for progressive glaucomatous optic neuropathy, which may have applicability in reducing the number of visual fields requiring testing, and thus shorten the testing process, according to the study.
The statistical method for predicting optic neuropathy used in the study was found to have an average sensitivity of 65% and specificity of 87%, according to the study.